Jenifer MacLean
Contact Information:
I am an experienced and agile Research Scientist with education and experience in both Physical Chemistry and Pharmaceutical Chemistry. My main areas of expertise are in battery research and the formulation development, preparation and advancement of small molecules in the Pharmaceutical Industry. I am an expert in the use of analytical instrumentation utilized in the identification and characterization of small molecules. I champion the development and use of green chemistry methods as a standard for research as this is something personally important to me.
I strive to instill trust in my personal brand as well as that of my company, Social Dragon utilizing communication skills that produce category-leading interest and awareness ensuring buy-in at all levels.
I am recognized as a take-charge leader and talented trainer. I wrote the training manual outlining training methods for all new hires into the Small Molecule Pharmaceutics group at Amgen. I thoroughly enjoy teaching people and providing them with the tools needed to achieve high performance.
I enjoy being innovative and resourceful and I come with a reputation for quickly learning and mastering new skills, technologies, and instruments.
I enjoy being innovative and resourceful and I come with a reputation for quickly learning and mastering new skills, technologies, and instruments.
I have been Six Sigma Green Belt trained and I'm even fluent in German.
Professional Experience
I'm currently running my start up, Social Dragon. Traditional marketing alone isn't enough to get the attention you need to attract new customers. Social Media is now a must for any business looking to attract new customers and keep the current ones.
At Social Dragon we work with our clients to plan a cost effective Social Media strategy custom designed for each individual business. What works for you doesn't necessarily work for everyone else so we take the time to understand your business plan and who your target customers are. And then we show you how to engage with them in the most effective manner.
We'll not only provide you with a monthly report detailing traffic and engagement metrics, we'll show you directly the effect our efforts have on reaching your business goals. Additionally, we work with complete transparency with our clients. Your accounts are your accounts. You'll have complete access to your passwords and administrative rights to your website and all Social Media accounts. We'll even sit down with you and show you how to edit your website and post to your Social Media accounts all on your own, if you're so inclined.
As the owner, founder and creator of my own company I do everything required to run a business including:
Website Design - The design and constant tweaking of my own business page, as well as those of my clients. I even teach my clients how to manage their own sites once I've designed it.
Social Media Advertising and Marketing - To increase the presence of my client's businesses out in the virtual world I use Twitter, Blogs, LinkedIn, Facebook, Google+, Pinterest, and Yahoo/Bing. These methods have helped me build my customer base and brand recognition. I
SEO - I manage SEO for my clients according to Google's new Penguin algorithm focused on content rather than keyword stuffing. In less than a week I managed to bring my business page, when searched for by name, from page 5 to page 1 of search results in Google. I'm kind of proud of that one...
General Business Management - I manage all financial aspects, sales and invoicing. I designed and implemented a customer service program, wrote the business plan and every SOP. I am the IT, Legal and HR departments. I also make the coffee.
While running my start up I was working at:
Monsanto from Jan 2012 to October 2012as the Seed Technology Trial Coordinator
After less than a year I got laid off again but I learned a lot working for Monsanto and appreciated the time I spent there.
I managed all aspects of the field trials designed to investigate the effect various seed treatments have on vegetables. Basically, scientists in the group develop new treatments for seeds aiming for various effects and I carry out the experiment in the real world so we can see how well it does. I also had a research project of my own.
In less than a year I managed to:
Achieve a cost savings of about 75% in the reduction of testing and packaging of seed accomplished by initiating a study of the pepper seed sorting procedure into 4 sizes and restructuring the process into sorting for one size only. This project was part of the Six Sigma Green Belt certification program. I wasn't able to finish the final report before I was laid off so I didn't earn the certification. But, I did all the training and finished the project, the results of which are being implemented.
Increased the number of field trials initiated in 2012 to just over 75 in multiple countries compared to 15 in 2011. I restructured the trial design, planning and implementation process and wrote the new protocol.
Designed and initiated a project management program for the Seed Technology Experimental Field Trials. Implemented processes of my own design for planning and executing trials, building and maintaining timelines and the collection and assimilation of data.
Authored the fundamental SOP document to establish best practices in trial planning and execution and trained group/team members in the new procedures.
Identified a disruptive technology for use in Seed Technology research. I can't tell you what it is. But it's pretty neat. But since I'm not there anymore I don't know if they'll ever use it.
From 2003 to 2012 I worked at:
Amgen Inc.
During the time I spent at Amgen I managed to:
I Published a green chemistry method developed as a scalable process to amorphize and stabilize crystalline compounds, which is no easy task. Utilization of this green method reduced solvent purchase and disposal costs by up to 30% for this process.
I redesigned a problem oncology formulation dramatically increasing drug exposure from 42% to 94%. Not only did this improve our results but it kept the project from being cancelled and significantly reduced the amount of drug, ie: money, required for each study. It was really a matter of increasing solubility of the API.
By creating a a vehicle inventory system that greatly improved the availability of fresh vehicle required for daily dosing formulations I achieved a 50% reduction in waste lowering operating costs for both my lab and the lab producing the vehicle we used.
Less than 6 months after joining my group I was selected to train new hires in all lab procedures including formulation development. I developed a training curriculum and wrote a training manual to ensure consistency in what was being taught. I trained every new hire to the group, guiding them on the best formulation techniques and operational procedures found in small molecule drug development.
I cross trained in various departments in addition to performing my daily job. I trained others on the instruments I had expertise in and was, in turn, trained in other departments. I worked with Analytical Chemistry to learn Dissolution, how to determine polymorphs and salts of potential drug candidates using Symyx instrumentation and I learned the techniques and instrumentation employed by the Forensics group. This last one was by far the most fun.
I've also done this:
As a Research Associate at Amgen from 2004 to 2007 I built a reputation as the department expert in emulsion research and developed the emulsion formulation standard that is still in use.
I Published a green chemistry method developed as a scalable process to amorphize and stabilize crystalline compounds, which is no easy task. Utilization of this green method reduced solvent purchase and disposal costs by up to 30% for this process.
I redesigned a problem oncology formulation dramatically increasing drug exposure from 42% to 94%. Not only did this improve our results but it kept the project from being cancelled and significantly reduced the amount of drug, ie: money, required for each study. It was really a matter of increasing solubility of the API.
By creating a a vehicle inventory system that greatly improved the availability of fresh vehicle required for daily dosing formulations I achieved a 50% reduction in waste lowering operating costs for both my lab and the lab producing the vehicle we used.
Less than 6 months after joining my group I was selected to train new hires in all lab procedures including formulation development. I developed a training curriculum and wrote a training manual to ensure consistency in what was being taught. I trained every new hire to the group, guiding them on the best formulation techniques and operational procedures found in small molecule drug development.
I cross trained in various departments in addition to performing my daily job. I trained others on the instruments I had expertise in and was, in turn, trained in other departments. I worked with Analytical Chemistry to learn Dissolution, how to determine polymorphs and salts of potential drug candidates using Symyx instrumentation and I learned the techniques and instrumentation employed by the Forensics group. This last one was by far the most fun.
I've also done this:
As a Research Associate at Amgen from 2004 to 2007 I built a reputation as the department expert in emulsion research and developed the emulsion formulation standard that is still in use.
As a Battery Engineer at Zinc Matrix Power from 2003 to 2004 I worked as part of a team to develop a novel membrane separator designed to maximize electron exchange between the cathode and anode.
I also worked as an undergrad at UCLA in the Tolbert Research Group as a Research Assistant from 2001 to 2002. I very happily worked on a project that was later published. As part of the team I developed the method for creating a novel cathode material for high-powered nano-scale batteries. I was also the first to determine the structure of vanadium oxide nanorolls and I characterized the mechanism for nanoroll ion exchange.
I'm adventurous and inquisitive so I've had a winding career path that has let me to where I am today. Here are some of the stops along the way:
I'
Lab Assistant at Moorpark College Chemistry Department
Volunteer Tutor - Calculus, Chemistry, Physics, Physical Chemistry
Volunteer Tutor - Calculus, Chemistry, Physics, Physical Chemistry
Assistant Designer at Alleen Morris Designs, Women's Swimwear
Assistant Designer at Lane Davis Designs, Women's Couture
Founder/Owner, BJ Baskets, My first business
Custody Assistant, Los Angeles County Sheriff’s Department
MS, Pharmaceutical Chemistry, University of Kansas, Lawrence, KS
BS, Chemistry with specialization in Physical Chemistry, University of California, Los Angeles, CA
My Posters:
Formation of physically stable amorphous complex of an acidic drug with Neusilin. Jenifer MacLean, Cesar Medina, Dominick Daurio, Fernando Alvarez-Nunez, Eric Munson, and Karthik Nagapudi 2011 SMP&PD Annual Symposium
Manufacture of Pharmaceutical Relevant Material via Mechanochemistry using Twin Screw Extrusion - Cocrystals and Salts. Dominick Daurio, Jenifer MacLean, Cesar Medina, Lan Li, Karthik Nagapudi and Fernando Alvarez-Nunez. 2010 SMP&PD Annual Symposium
Manufacture of Pharmaceutically Relevant Materials via Mechanochemistry using Twin Screw Extrusion. Dominick Daurio, Jenifer MacLean, Cesar Medina, Lan Li, Karthik Nagapudi and Fernando Alvarez-Nunez. AAPS 2010
Stabilization of the Amorphous Phase of Sulindac with Neusilin: Mechanism, Performance and Scalability.
Jenifer MacLean, Cesar Medina, Dominick Daurio, Fernando Alvarez-Nunez, Eric Munson, and Karthik Nagapudi. 2009 SMP&PD Annual Symposium
Evolution of Griseofulvin Crystalline Phase to Nuclei-Rich Amorphous Phase Upon Cryogenic Milling.
Lei Zhu, Jenifer MacLean, Tian Wu, Karthik Nagapudi. 2009 SMP&PD Annual Symposium
My Publications:
The Relationship Between Nanoscale Structure and Electrochemical Properties of Vanadium Nanorolls Dong Sun, Chai Won Kwon, George Baure, Erik Richman, Jenifer MacLean, Bruce Dunn and Sarah Tolbert. Advanced Functional Materials 2004, 14, No.12, (1197 – 1204) December
